Table 1.
Author | n | Duration | Paracetamol use | Cases of HTN | Relative risk |
---|---|---|---|---|---|
Dedier et al. 35 | 51 630 | 8 years | Days per month | ||
None | 4037 | 1.00 | |||
1–4 | 2959 | 1.07 | |||
5–14 | 1033 | 1.22 | |||
15–21 | 317 | 1.31 | |||
>22 | 457 | 1.2 | |||
Curhan et al. 36 | 80 020 | 2 years | Days per month | ||
None | 369 | 1.00 | |||
1–4 | 661 | 1.19 | |||
5–14 | 229 | 1.37 | |||
15–21 | 62 | 1.62 | |||
≥22 | 72 | 2.00 | |||
Kurth et al. 38 | 8 229 | 14 years | Cumulative use over 14 years | ||
<12 | 1204 | 1.00* | |||
12–1499 | 607 | 0.86 (0.77–0.95)* | |||
1500–2499 | 87 | 1.17 (0.93–1.46)* | |||
≥2500 | 97 | 1.08 (0.87–1.34)* | |||
Forman et al. 39 | 16 031 | 2 years | Days per week | ||
0 | 1743 | 1.00 | |||
1 | 47 | 1.00 | |||
2–3 | 69 | 1.00 | |||
4–5 | 36 | 1.59 | |||
6–7 | 50 | 1.34 |
Hazard ratio. HTN, hypertension.