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Biomechanical analysis of intact and fractured tibias from WT (n = 13) and Col2a1-ICAT (n = 10) mice using the four-point bending test 5 weeks after surgery. The maximum full load and Young’s modulus of fractured tibias from Col2a1-ICAT mice is significantly reduced when compared to that of tibias from either intact Col2a1-ICAT or fractured WT mice (*p < 0.05, **p < 0.01).
