Quantitative-PCR analysis of the expression of genes associated with the genes involved in cartilage formation and hypertrophy (A), bone remodeling (B), transcription of chondrogenesis- and ossification-associated genes (C), and angiogenesis (D) in fracture calluses of WT and Col2a1-ICAT mice at 5, 7, 9, 12, 14, 21, and 28 days after surgery (*p < 0.05 for the peak values of gene expression in calluses of WT versus Col2a1-ICAT mice during the healing process). Eight mice were tested in each time point.