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. 2013 Jun 6;2013:928271. doi: 10.1155/2013/928271

Figure 4.

Figure 4

Concentration-response curves in arteries without vascular endothelium obtained for phenylephrine in the absence and presence of low-dose aspirin, high-dose aspirin, and ticagrelor coadministered with 2-MeS-ADP. Points and whiskers display mean values ± standard deviations. A curve for PHE represents a control curve for TIC, ASA (L), and ASA (H) while curves for ASA (L) and ASA (H) constitute control curves for ASA (L) + TIC and ASA (H) + TIC, respectively. ASA (H): high-dose aspirin; ASA (L): low-dose aspirin; Ea/Em: % of maximal response; PHE: phenylephrine; TIC: ticagrelor; 2-MeS-ADP: stable analogue of adenosine diphosphate; *a value of P < 0.05 when comparing the control curve for points of effect between 20% and 80% of the maximal response.