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Effect of well-controlled or poor glycaemic control on intracellular ROS measurements in diabetes. Flow cytometry of H2DCF-DA-loaded monkey platelets in PRP either untreated (no add.) or treated with 10 μg/mL CRP or 5 μM TRAP. Syk inhibition by 5 μM BAY61-3606 (BAY) reduces GPVI-induced ROS generation in all monkey groups. Data are from six monkeys in each group. ***P < 0.001.
