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. Author manuscript; available in PMC: 2013 Jun 23.
Published in final edited form as: Biochim Biophys Acta. 2011 Sep 14;1821(3):502–512. doi: 10.1016/j.bbalip.2011.08.019

Table I.

Plasma Lipid and Apolipoprotein Concentrations in Chow- and Diet-Fed Mice

Genotype (n) Plasma
Cholesterol
(mg/dL)
Plasma
Triglycerides
(mg/dL)
Human
Wild-type ApoA-I
(mg/dL)
Human
L159R ApoA-I
(mg/dL)
Mouse
ApoE
(mg/dL)
  CHOW
DKO (10) 190 ± 19a 126 ± 26a - - 7 ± 2a
WT-DKO (53) 195 ± 8a 98 ± 8a 100 ± 6a - 5 ± 1a
FIN-DKO (37) 200 ± 13a 120 ± 10a - 5 ± 1a 17 ± 3b
WT FIN-DKO (24) 169 ± 5a 86 ± 5b 113 ± 10a 25 ± 2b 10 ± 2a,b
  DIET
DKO (24) 710 ± 19a 226 ± 53a - - 22 ± 2b
WT-DKO (15) 1201 ± 68b 347 ± 51a 126 ± 16a - 21 ± 3b
FIN-DKO (23) 750 ± 32a 265 ± 14a - 9 ± 2a 36 ± 2c
WT FIN-DKO (9) 850 ± 46c 375 ± 55a 129 ± 19a 38 ± 5c 48 ± 3c

Plasma cholesterol, triglyceride and apolipoprotein values were determined as described in “Materials and Methods.” All values represent the mean ± SD. The number of animals analyzed for each genotype is shown in parenthesis. No statistically significant differences between genders were noted among any of the 4 genotypes. Superscripts with different letters indicate significant differences at ρ < 0.05.