Table 2.
Hazard ratio | 95% CI | P Value | |
---|---|---|---|
Multiple mutations vs. single mutation* | 2.28 | 1.17–4.42 | 0.015 |
Multiple mutations in single gene vs. single mutation | 3.15 | 1.30–7.61 | 0.010 |
Multiple mutations involving different genes vs. single mutation | 1.68 | 0.69–4.11 | 0.256 |
Female | 2.25 | 1.01–5.02 | 0.048 |
QTc ≥ 500msec | 2.22 | 1.04–4.74 | 0.041 |
Models were adjusted also for time dependent beta blockers, and QTc missing.
The effects of multiple mutations in single gene and in multiple genes were assessed in a separate model.