Table 1.
Pre-Randomization Patient Characteristics
| No ACE-Inhibitor (N=9) | ACE-Inhibitor (N=11) | |
|---|---|---|
| Age (months) | 20.8±6.5 | 13.7±3.5 |
| Gender, Male, N(%) | 6 (66.7) | 7 (63.6) |
| Race, Caucasian, N(%) | 7 (77.8) | 9 (81.8) |
| Weight (kg) | 9.1±1.2 | 7.8±1.2 |
| Weight (percentile for age) | 11.7±5.8 | 20.2±8.4 |
| Mean arterial pressure (mmHg) | 74.4±4.6 | 69.5±3.8 |
| Pulse pressure (mmHg) | 43.7±3.2 | 40.9±3.6 |
| Heart Rate (BPM) | 123.1±5.9 | 125.9±3.1 |
| Pulse oximetry saturation (%) | 82.8±2.5 | 85.2±2.3 |
| Hematocrit (%) | 45.3±0.8 | 44.7±2.3 |
| Platelet count (k/μl) | 397.8±24.7 | 317.2±14.9* |
| Creatinine (mg/dl) | 0.41±0.02 | 0.43±0.04 |
| Potassium (meq/L) | 4.7±0.2 | 4.6±0.2 |
| Single ventricle physiology, N(%) | 9 (100) | 8 (72.7) |
| Failure to Thrive, N (%) | 4 (44.4) | 6 (54.5) |
| ACE Inhibitor Dose (mg/kg/day) | 0.25±0.04 | 0.24±0.03 |
| Other Preoperative Medications | ||
| Aspirin, N (%) | 9 (100) | 7 (63.6)† |
| Spironolactone, N (%) | 3 (33.3) | 2 (18.2) |
| Digoxin, N (%) | 5 (55.6) | 4 (36.4) |
| Enoxaparin, N (%) | 2 (22.2) | 1 (9.1) |
| Furosemide, N (%) | 7 (77.8) | 8 (72.7) |
ACE indicates angiotensin converting enzyme.
*
P<0.05,
†
P=0.09 versus No ACE inhibitor.