Table 2.

Grey-matter volume comparisons.

Region	HR−C Vs HR+C	HR−C Vs HC	HR+C Vs HC
	F(1,91 ),p	F( 1,136),p	F(1,113), p
Intra cranial volume	1.79, 0.195	0.9, 0.693	1.2, 0.429
Left Heschl’s gyrus	3.81, 0.053	2.99, 0.08	p>0.2
Right Heschl’s gyrus	4.92, 0.032	11.22, 0.000	p>0.2
Left supramarginal gyrus	3.28, 0.071	20.06, 0.000	p>0.2
Right supramarginal gyrus	p>0.2	6.05, 0.015	p>0.2
Right angular gyrus	p>0.2	18.1, 0.000	3.12, 0.070
Left superior parietal gyrus	p>0.2	3.43, 0.065	3.62, 0.059
Right superior parietal gyrus	p>0.2	8.23, 0.004	4.22, 0.039
Right middle frontal gyrus	p>0.2	6.78, 0.010	p>0.2
Right superior frontal gyrus	p>0.2	3.96, 0.048	p>0.2
Left inferior frontal gyrus	7.32, 0.001	12.32, 0.000	p>0.2
Right inferior frontal gyrus	4.05, 0.042	3.32, 0.071	p>0.2
Left hippocampus	4.18, 0.039	8.79, 0.000	p>0.2
Right hippocampus	4.11, 0.041	8.02, 0.000	p>0.2
Left caudate	4.71, 0.036	9.09, 0.000	p>0.2
Right caudate	6.45, 0.011	14.21, 0.000	p>0.2
Left thalamus	p>0.2	5.67, 0.018	p>0.2
Right thalamus	p>0.2	6.68, 0.012	p>0.2

F statistics and p values for ANCOVAs controlling for ICV, age and gender comparing brain regional grey matter volumes between groups. HR−C are seen to show volumetric deficits compared to HC and HR+C groups. HR+C showed trend-level deficits compared to HC for right angular and superior parietal cortices. (see Fig. 2).