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Inhibition of P-gp-mediated rhodamine-123 efflux from peripheral white blood cells by different tariquidar concentrations added ex vivo. Note that the x-axis is in a logarithmic scale. The data present the mean±SD of the results obtained with whole blood from the same 5 volunteers who underwent the paired PET scans. The mean EC50 was 0.5±0.2 ng/mL.
