Table 2.
The comparison of measures among 3 groups of mouse (experiment B)
| Alive (n = 7) | Euthanized (n = 21) | Spontaneous death (n = 32) | Pa | |
| Baseline temperature (°C; day 0) | ||||
| Mean ± SE | 36.5 ± 0.26 | 37.0 ± 0.14 | 36.8 ± 0.13 | 0.21 |
| Minimum, maximum | 35.1, 37.3 | 35.6, 38.3 | 34.2, 38.2 | |
| Lowest subcutaneous temperature (days 1–30) | ||||
| Mean ± SE | 35.5 ± 0.20 | 30.3 ± 1.1 | 32.3 ± 0.6 | 0.009 |
| Minimum, maximum | 34.5, 35.9 | 22.5, 36.0 | 26.0, 36.7 | |
| Largest decrease of subcutaneous temperature from baseline | ||||
| Mean ± SE | −1.0 ± 0.2 | −6.7 ± 1.1 | −4.4 ± 0.6 | 0.005 |
| Minimum, maximum | –1.8, –0.4 | –15, –0.6 | –11, 1.3 | |
| Baseline weight (g; day 0) | ||||
| Mean ± SE | 20.0 ± 0.56 | 19.9 ± 0.25 | 20.1 ± 0.25 | 0.89 |
| Minimum, maximum | 18.5, 22.2 | 18.0, 22.0 | 17.6, 23.4 | |
| Weight gain rate (g/d) | ||||
| Mean ± SE | 0.03 ± 0.02 | −0.58 ± 0.08 | −0.62 ± 0.04 | <0.0001 |
| Minimum, maximum | –0.05, 0.07 | –1.00, 0.02 | –1.2, –0.17 | |
| Highest (worst) activity score | ||||
| Mean ± SE | 2.3 ± 0.2 | 2.7 ± 0.1 | 2.3 ± 0.1 | 0.02 |
| Minimum, maximum | 2, 3 | 2, 3 | 1, 3 | |
a
P value reflects the comparison among all 3 groups.