TABLE 2.

Three-Way Interaction of Sex, Diagnostic Group, and Cue Condition in Cocaine-Dependent and Comparison Women and Men in a Study of Stress- and Cue-Induced Craving^a

Region	Volume (mm³)	Volume (Voxels)	Talairach Coordinates

			x	y	z	Mean t	SD
Right insula, hippocampus, amygdala, putamen, and Brodmann areas 38 and 20	15,437	572	37	−7	−9	3.75	0.57
Right Brodmann areas 38 and 20	3,773	140	32	−3	−26	3.88	0.68
Right putamen	1,748	65	27	−10	0	3.57	0.40
Right amygdala, hippocampus	2,078	77	27	−4	−12	3.79	0.44
Right insula	3,557	132	37	3	3	3.49	0.32
Right Brodmann area 44	1,666	62	49	10	2	3.70	0.45
Right Brodmann area 22	2,615	97	36	−3	−8	4.03	0.69
Caudate, anterior cingulate, and Brodmann areas 47 and 46	19,802	733	−20	31	6	3.90	0.64
Left Brodmann area 10	8,175	303	−30	41	18	3.94	0.72
Left and right caudate, ventral striatum	4,027	149	1	17	−2	3.81	0.55
Left Brodmann area 45	4,430	164	−28	34	6	3.94	0.59
Left Brodmann area 46	2,321	86	−44	38	6	3.99	0.64
Left anterior cingulate	849	31	−13	40	14	3.59	0.35
Posterior cingulate and Brodmann areas 39 and 7	63,152	2339	8	−51	35	4.16	0.93
Left Brodmann area 6	11,571	429	−19	−6	50	4.30	1.20
Right Brodmann area 21, fusiform, Brodmann area 19	15,787	585	41	−54	−2	3.85	0.67

The table lists the results of the family-wise error whole brain corrected voxel-based analyses (p<0.05) for the three-way interaction of sex, diagnostic group (with and without cocaine dependence), and cue condition (stress, drug/alcohol-related, and neutral-relaxing).