Table 2.
Human CARMA1 | S109 | T110 | S551 | S552 | S555 | S565 | S608 | S637 | S645 |
Mouse CARMA1 | S116 | T117 | S563 | S564 | S567 | S577 | S620 | S649 | S657 |
Kinase | CaMKII | PKCθ | HPK1 | PKCθ | IKKβ | ? | CK1α | PKCθ | PKCθ |
Effect of Mutation | |||||||||
NF-κB | ↓ | ↓ | ↓ | ↓ | ↓ | ↓ | ↑ | Normal | ↓ |
JNK | ? | ↓ | ? | ↓ | ↓ | ? | Normal | ? | ↓ |
Adapted from14.