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. Author manuscript; available in PMC: 2013 Jun 24.
Published in final edited form as: Vaccine. 2007 Mar 22;25(21):4183–4192. doi: 10.1016/j.vaccine.2007.03.008

Figure 4. The pattern of anti-CEA-scFv expression in VNP/GS18IND as probed with atomic force microscopy.

Figure 4

(A) The image of a single bacteria in AFM with descrete regions denoted as P (pole), I (intermediate region) and M (middle region). (B) Histogram (obtained from 400 force curves) of rupture forces recorded with a CEA-coated tip. Green bars represent rupture forces for a pole (P) region, orange bars – (I) and red bars – (M). The force-distance relationships have a slightly non-linear character due to polymer extension. Data represent a single measurement performed on at least two bacterial cells representative of two independent experiments.