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. Author manuscript; available in PMC: 2013 Jun 24.
Published in final edited form as: Vaccine. 2007 Mar 22;25(21):4183–4192. doi: 10.1016/j.vaccine.2007.03.008

Figure 6. Effects of the modified VNP on MC38CEA tumor growth.

Figure 6

(A) Seven-day established MC38CEA tumors were injected i.v. with 2 × 106 cfu VNP (▲), VNP/GS18 (▼) or VNP/GS18IND (◆) or PBS (CTRL■). Tumor growth was measured every 2 – 3 days by measurement the longest perpendicular diameters and data is presented as tumor area (mm2). For VNP/GS18 and VNP/GS18IND P<0.001 vs control. Data represent average values from two independent experiments on total 10 mice per group. (B) Representative photo of tumor (upper panel) and spleen (lower panel) from mice treated with PBS (CTR) or VNP/GS18IND (VAC).