Table 3.
Cost-Effectiveness of Supplemental Immunization Activities (SIAs), Compared With Other Public Health Interventions
| Disease or condition | Cost-effectiveness in sub-Saharan Africa, US$/DALY | Intervention |
| SIAs for measles in Uganda | 1.50 | SIAs every 3 years covering 95% of children aged 12–59 months |
| Malaria | 7 | Intermittent preventive treatment in pregnancy with drug other than sulfadoxinepyrimethamine |
| African trypanosomiasis | 10 | Melarsoprol |
| Malaria | 11 | Insecticide-treated bednets |
| African trypanosomiasis | 15 | Case finding and treatment |
| Malaria | 17 | Residual household spraying |
| Malaria | 19 | Intermittent preventive treatment in pregnancy with sulfadoxinepyrimethamine |
| African trypanosomiasis | 20 | Eflornithine |
| Integrated management of childhood illness | 39 | Integrated management of childhood illness |
| HIV/AIDS | 57 | Diagnosis and treatment of sexually transmitted infections |
| Diabetes mellitus | 60 | Lifestyle intervention (prevention of type 2 diabetes mellitus) |
| HIV/AIDS | 82 | Condom promotion and distribution |
| HIV/AIDS | 84 | Blood and needle safety |
| Maternal mortality | 87 | Improved quality of comprehensive emergency obstetric care |
| Maternal mortality | 88 | Increased primary care coverage |
| Tuberculosis and HIV/AIDS | 121 | Prevention and treatment of tuberculosis coinfection |
NOTE. Data on SIAs in Uganda are from the current study; remaining data are from Jamison et al 2006 [18]. DALY, disability-adjusted life year; HIV, human immunodeficiency virus.