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Design and outcomes of phase II trials SPRINT (Serine Protease Inhibitor Therapy) and PROVE (Protease Inhibitor for Viral Evaluation) studies of boceprevir (BOC) and telaprevir (TVR). PIFN indicates peginterferon alfa; R, ribavirin; SOC, standard of care (peginterferon alfa and ribavirin); SVR, sustained virologic response. Compiled from McHutchison et al, Hezode et al, and Kwo et al.13-15
