| ORb | P value | ||
|---|---|---|---|
| Main effects | |||
| FAQ (SD = 1.00) | |||
| Difficulty with complex tasks to independence (2-1) | 22.34 | <.001 | |
| Difficulty with basic tasks to complex tasks (3-2) | 1.51 | <.001 | |
| Dependent to difficulty with basic tasks (4-3) | 0.76 | .236 | |
| Reversed MMSE (SD = 6.47) | |||
| Difficulty with complex tasks to independence (2-1) | 5.52 | <.001 | |
| Difficulty with basic tasks to complex tasks (3-2) | 0.62 | .002 | |
| Dependent to difficulty with basic tasks (4-3) | 0.43 | .04 | |
| NPI-Q (SD = 4.25) | |||
| Difficulty with complex tasks to independence (2-1) | 2.04 | <.001 | |
| Difficulty with basic tasks to complex tasks (3-2) | 0.71 | .023 | |
| Dependent to difficulty with basic tasks (4-3) | 0.81 | .632 | |
| Interaction terms | |||
| FAQ × revMMSE (SD = 17.80) | |||
| Difficulty with complex tasks to independence (2-1) | 0.07 | <.001 | |
| Difficulty with basic tasks to complex tasks (3-2) | 3.3 | <.001 | |
| Dependent to difficulty with basic tasks (4-3) | 4.67 | <.001 | |
| NPI-Q × revMMSE (SD = 63.14) | |||
| Difficulty with complex tasks to Independence (2-1) | 0.54 | .001 | |
| Difficulty with basic tasks to complex tasks (3-2) | 1.32 | .268 | |
| Dependent to difficulty with basic tasks (4-3) | 0.52 | .283 | |
| FAQ × NPI-Q (SD = 9.85) | |||
| Difficulty with complex tasks to Independence (2-1) | 0.28 | <.001 | |
| Difficulty with basic tasks to complex tasks (3-2) | 1.86 | <.001 | |
| Dependent to difficulty with basic tasks (4-3) | 1.54 | .276 | |
| Third order (SD = 172.35) | |||
| Difficulty with complex tasks to Independence (2-1) | 3.71 | <.001 | |
| Difficulty with basic tasks to complex tasks (3-2) | 0.58 | .05 | |
| Dependent to difficulty with basic tasks (4-3) | 1.7 | .362 | |
Abbreviations: ADC, Alzheimer’s disease Center; MMSE, minimental state examination; FAQ, functional activities questionnaire; NPI-Q, Neuropsychiatric Inventory questionnaire; OR, odds ratio; SD, standard deviation.
a Complete data analysis of 14 522 respondents. All analyses controlled for age, age squared, sex, years of education, and ADC.
b Standardized coefficients adjust for the difference in scale and are interpreted as the increased likelihood of being at a higher level of dependence for 1 SD increase.