Table 3.
High resolution peripheral quantitative computed tomography in T2DM and controls
| ± SD
| |||
|---|---|---|---|
| T2DM (N=14) | Controls (N=14) | p value | |
| Age (years) | 64±6 | 63±5 | NS |
| BMI (kg/m2) | 31.7±8 | 30.0±8 | NS |
| Race | African American: 7 | African American: 7 | |
| Hispanic and non-Hispanic white: 7 | Hispanic and non-Hispanic white: 7 | ||
| Fasting plasma glucose (mg/dl) | 132±44 | 88±12 | 0.001 |
| Hgb A1c (%) | 8.2±2 | ||
| Radius | |||
| Mean area (mm2) | 244±60 | 256±49 | NS |
| Cortical area (mm2) | 51±11 | 49±15 | NS |
| Trabecular area (mm2) | 189±60 | 201±48 | NS |
| Total density (mgHA/cm3) | 310 ±87 | 284 ±75 | NS |
| Ct density (mgHA/cm3) | 884 ±88 | 845±88 | NS |
| Ct thickness (mm) | 781±213 | 726±227 | NS |
| Trabecular density (mgHA/cm3) | 126 ±42 | 121 ±35 | NS |
| Trabecular bone volume (%) | 9.7±3 | 10.1±3 | NS |
| Trabecular number (1/mm) | 1.7±0.4 | 1.6±0.4 | NS |
| Trabecular thickness (mm) | 60±11 | 62±8 | NS |
| Trabecular separation (mm) | 543 ±154 | 586±180 | NS |
| SD of 1/trabecular numbera | 269±115 | 321 ±211 | NS |
| Tibia | |||
| Mean area (mm2) | 708±139 | 711±105 | NS |
| Cortical area (mm2) | 94±22 | 105±23 | NS |
| Trabecular area (mm2) | 584±138 | 571±106 | NS |
| Total density (mgHA/cm3) | 243±58 | 251±49 | NS |
| Ct density (mgHA/cm3) | 833±71 | 812 ±62 | NS |
| Ct thickness (mm) | 931 ±240 | 1009±202 | NS |
| Trabecular bone volume (%) | 11.2±4 | 11.6±3 | NS |
| Trabecular density (mgHA/cm3) | 135±43 | 139±37 | NS |
| Trabecular number (1/mm) | 1.6±0.4 | 1.6±0.3 | NS |
| Trabecular thickness (mm) | 70±14 | 71±13 | NS |
| Trabecular separation (mm) | 588±154 | 558±96 | NS |
| SD of 1/trabecular numbera | 280±97 | 290±113 | NS |
a
SD of 1/trabecular number is a measure of trabecular network heterogeneity, or the irregularity of the trabecular spacing.