Figure 4. Origin of TRIM5-CypA gene fusions in macques and owl monkeys.
(A) Retroposition of CypA into an intron of the TRIM5 gene from macaques and the resulting fusion gene is shown (similar to the process displayed in Fig. 2A). (B) An independent retroposition of CypA into the UTR of TRIM5 in owl monkeys is shown, also resulting in a new TRIM5-CypA fusion gene. Please refer to Fig. 2 for the colour code and to the main text for details.