Table I.
Major Crystallographic or NMR Structures (Complete or Partial) of Unique Spliceosomal Protein or RNA Components Determined to Date
| snRNP | Unique protein or RNA structures (complete or partial) determined |
|---|---|
| U1 | U1 snRNP, U1-70K, U1A, U1C, and Prp40 |
| U2 | SF3a components (Prp9, Prp11, Prp21), SF3b components (SF3b155, SF3b14, SF3b2, SF3b4), U2AF35, U2AF65, PUF60, SPF45, U2 A', U2 B'', and BPS/U2 snRNA |
| U4 | U4 snRNP Sm core, and U4 snRNA |
| U5 | Prp8, Brr2, Aar2, 15K, and 52K |
| U6 | Prp24, U6 snRNA, and Lsm3–7 |
| U4/U6.U5 | Snu66, 15.5K, Prp31, and Snu13p |
| U4/U6 | Prp3, Cyclophilin H, and Prp4 |
| Components common to all snRNPs | Sm D1, D2, D3, B, E, F, and G |
| Non-snRNP associated | UAP56, SF1, Pml1, Dim2, Cwc2, Prp19, Rbm22, Prp43, Prp18, Prp22, and U2/U6 snRNA |
When more than one homologous structure of a protein is available, only the protein from one species is listed. More details of the structure are provided in Supporting Information Table I.