Table 2.
Levels of phospholipids and cholesterol in RBC membranes obtained from control subjects and from patients with type 2 DM and/or cirrhosis.
| Parameter | Healthy (n = 60) | Diabetes (n = 60) | Cirrhosis (n = 70) | Diab + Cirrhos (n = 25) |
|---|---|---|---|---|
| PS (nmoles/mg) | 40 ± 14 | 34 ± 10 | 30 ± 8* | 63 ± 14∗,∗∗∗ |
| PI (nmoles/mg) | 46 ± 10 | 45 ± 11 | 50 ± 12 | 126 ± 26∗,∗∗∗ |
| PC (nmoles/mg) | 62 ± 14 | 63 ± 16 | 77 ± 17* | 194 ± 36∗,∗∗∗ |
| PE (nmoles/mg) | 23 ± 6 | 27 ± 6 | 26 ± 6 | 70 ± 10∗,∗∗∗ |
| Cholesterol (nmoles/mg) | 17 ± 4 | 18 ± 5 | 25 ± 6* | 41 ± 6∗,∗∗∗ |
Results are expressed as mean ± SD of determinations done in RBC membranes from controls (n = 60), patients with type 2 DM (n = 60), cirrhotic patients (n = 70), and diabetic patients with cirrhosis (n = 25). PC: phosphatidylcholine; PE: phosphatidylethanolamine; PI: phosphatidylinositol; PS: phosphatidylserine; Diab + Cirrhos: diabetes + cirrhosis. Statistical significance: *P < 0.01, versus control; **P < 0.01, versus DM or versus cirrhosis; ***P < 0.01, versus both the diabetes and cirrhosis groups, separately.