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. Author manuscript; available in PMC: 2013 Jun 24.

Published in final edited form as: Gene. 2009 Nov 26;451(0):45–53. doi: 10.1016/j.gene.2009.11.010

Fig. 2 — Homology analysis of Rgs4 5′-UTR and putative promoter. (A) Highly conserved 5′-UTR. Multiple alignment from various species by Clustal W method showing the shaded residues different from rabbit Rgs4 (upper panel) and the identity percentage between species (lower panel). (B) Sequence of rabbit Rgs4 promoter and partial exon-1. Putative transcription factor binding sites analyzed by MatInspector are highlighted with color. Sequence from the transcription start site is in capital case. NF-κB: nuclear factor kappa B; AP-1: activator protein 1; HSF: heat shock factor. (C) Evolutionary analysis of Rgs4 promoter. Nucleotide sequence alignment of rabbit Rgs4 promoter (−257 to −1) with human, mouse and rat demonstrating highly conserved region at the proximal promoter. The shaded residues exactly match rabbit Rgs4 promoter sequence.

Fig. 2 — Homology analysis of Rgs4 5′-UTR and putative promoter. (A) Highly conserved 5′-UTR. Multiple alignment from various species by Clustal W method showing the shaded residues different from rabbit Rgs4 (upper panel) and the identity percentage between species (lower panel). (B) Sequence of rabbit Rgs4 promoter and partial exon-1. Putative transcription factor binding sites analyzed by MatInspector are highlighted with color. Sequence from the transcription start site is in capital case. NF-κB: nuclear factor kappa B; AP-1: activator protein 1; HSF: heat shock factor. (C) Evolutionary analysis of Rgs4 promoter. Nucleotide sequence alignment of rabbit Rgs4 promoter (−257 to −1) with human, mouse and rat demonstrating highly conserved region at the proximal promoter. The shaded residues exactly match rabbit Rgs4 promoter sequence.