Figure 1.

Localization of recombination in PR-Cre and Amhr2-Cre oviducts and ovaries. The conditional gene recombination by Cre recombinase induced by the PR promoter (upper panel) or Amhr2 promoter (lower panel) was visualized by LacZ staining. R26R/PR-Cre females show recombination primarily in corpus luteum (CL), GCs and the isthmus of the oviduct (ith), while R26R/Amhr2-Cre females show recombination in the oviductal muscularis layer (Mus) and ovarian follicular GC. Tissues were harvested at the age of 60 days. Left panels are of lower magnification: left panel bars, 400 µm. Right panels are of higher magnification: bars, 100 µm. Ovi, oviduct; Ov, ovary; amp, oviductal ampulla; Mu, mucosa; Ser, serosa; UT, uterus.