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. 2013 Jun 3;110(25):10234–10239. doi: 10.1073/pnas.1303738110

Fig. 3.

Fig. 3.

HMP induces HIV-1 expression and replication. (A) Dose-dependent response of HIV-1 LTR expression to HMP. HIV-1 LTR expression in Jurkat 1G5 cells was quantified by luciferase assay. Data represent the fold induction of expression over untreated cells. Data shown are the mean of three independent experiments ± SEM. *P < 0.05; ANOVA, Dunnett. (B) Effect of HMP on replication of HIV-1 LAV from latently infected CD4+ T cells. HIV-1 LAV replication from ACH-2 cells was measured by ELISA for p24 antigen. Data shown are the mean four independent experiments ± SEM. *P < 0.05; ANOVA, Dunnett. (C) Effect of HMP on replication of HIV-1 NL4-3 from acutely infected CD4+ T cells. HIV-1 NL4-3 replication was measured by ELISA for p24 antigen. Data are represented as fold induction over untreated cells and are the mean of three individual experiments ± SEM. *P < 0.05 comparing MOIs or HMP concentrations versus untreated cells; ANOVA, Dunnett.