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HMP is required for activation of CD4+ T cells by Neisseria spp. (A) CD69 expression in response to Neisseria spp. hldA mutants and (B) to increasing concentrations of HMP. The proportion of cells expressing CD69 was determined by flow cytometry. Data are the mean of three individual experiments ± SEM. *P < 0.05 versus untreated; ANOVA, Dunnett.
