TABLE 2.
Hierarchical regression coefficients of IL-6 and other variables predicting recall performance.
| Variable values | Model Values | Change parameters | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| R2 | F | p | df | Δ R2 | Significance of F change |
|||||
| B | β | t Value | p | |||||||
| 1st STEP Age |
−.03 | −.29 | −2.93 | .004 | ||||||
| WTAR | .01 | .11 | 1.10 | .28 | ||||||
| Sex | −.33 | −.20 | −2.02 | <.05 | ||||||
| Diagnosis | −.33 | −.21 | −2.17 | .03 | ||||||
| MMSE | .18 | .25 | 2.43 | .02 | ||||||
| BMI | −.03 | −.02 | −.16 | .88 | ||||||
| .28 | 5.08 | <.001 | 6,77 | |||||||
| 2nd STEP Age |
−.03 | −.25 | −2.59 | .01 | ||||||
| WTAR | .01 | .12 | 1.20 | .23 | ||||||
| Sex | −.25 | −.15 | −1.54 | .13 | ||||||
| Diagnosis | −.26 | −.18 | −1.81 | .08 | ||||||
| MMSE | .22 | .30 | 3.07 | <.01 | ||||||
| BMI | <.01 | .02 | .20 | .84 | ||||||
| IL-6 | −.39 | −.30 | −3.08 | <.01 | ||||||
| .36 | 6.19 | <.001 | 7,76 | .08 | .003 | |||||
| FINAL MODEL Age |
−.02 | −.24 | −2.62 | .01 | ||||||
| WTAR | .01 | .11 | 1.23 | .22 | ||||||
| Sex | −.33 | −.20 | −2.17 | .03 | ||||||
| Diagnosis | 9.20 | 6.14 | 2.35 | .02 | ||||||
| MMSE | .41 | .58 | 3.92 | <.01 | ||||||
| IL-6 | −.30 | −.23 | −2.43 | .02 | ||||||
| MMSE x Dx | −.33 | −6.31 | −2.41 | .02 | ||||||
| .40 | 7.58 | <.001 | 7,79 | .04 | .02 | |||||
Notes: WTAR = Wechsler Test of Adult Reading, MMSE = Mini Mental State Examination, BMI = Body Mass Index Df for the t-tests correspond to the model’s denominator df given in the table. B = unstandardized betas, and β = standardized betas