Table 7.
Associations of the pigmentation SNPs identified in this study with melanoma riska
SNP | Reference allele | Test allele | OR (95% CI) | P-valueb |
---|---|---|---|---|
rs975739 | T | G | 0.93 (0.83–1.04) | 0.25 |
rs12421680 | G | A | 1.14 (1.01–1.27) | 0.02 |
rs3002288 | G | A | 1.02 (0.92–1.14) | 0.63 |
rs12520016 | T | G | 0.75 (0.59–0.96) | 0.02 |
rs7173419 | C | T | 0.88 (0.77–1.00) | 0.06 |
rs12203592 | C | T | 1.16 (1.01–1.34) | 0.03 |
aThe SNPs rs12202284 and rs8015138 were not available in the melanoma GWAS data.
bAdjusted for age, gender and the top two principal components.