Table 1.

Top 10 SEMA5A eQTLs regions with smallest minimum P

Chromosome	Start	End	eQTL genea	Left geneb	Right genec	# SNPsd	P-valuee
5	8 432 269	10 486 082	SEMA5A	MTRR	SNORD123	9	2 × 10−12
18	44 894 006	46 979 045	MIR4320,MYO5B	ACAA2	CCDC11	24	2 × 10−8
9	9 471 065	11 471 205	PTPRD	JMJD2C	MPDZ	2	3 × 10−8
14	22 917 791	24 973 124	CBLN3,KHNYN,NFATC4,NYNRIN	CMTM5	HCD1	5	5 × 10−8
4	167 781 602	169 841 939	–	SPOCK3	ANXA10	12	7 × 10−8
18	6 084 612	8 084 612	LAMA1	ARGHGAP28	LRRC30	1	2 × 10−7
20	39 042 867	41 132 741	–	CHD6	PTPRT	3	2 × 10−7
12	3 363 712	5 374 681	–	FGF23	FGF6	4	3 × 10−7
11	11 310 553	13 324 688	MICALCL	MICAL2	PARVA	5	4 × 10−7
1	206 278 586	208 290 185	KCNH1	HHAT	RCOR3	8	5 × 10−7

The top 10 eQTL regions with the smallest association P-value are shown here with their chromosome locations, overlapping or nearest Refseq genes, number of SNPs along with the smallest P-value in each eQTL regions. The coordinates are based on human genome assembly NCBI36/hg18.

^aeQTL gene that is located in the eQTL cluster. A “–” indicates that no gene overlaps the eQTL cluster.

^beQTL gene that is located on the left side (p-terminal) of the eQTL cluster.

^ceQTL gene that is located on the right side (q-terminal) of the eQTL cluster. Selected eQTL gene(s) bolded for each region.

^dNumber of SNPs that are located in the eQTL cluster.

^eMinimum P-value of association test of SEMA5A expression in the eQTL cluster.