Table 1.
Chromosome | Start | End | eQTL genea | Left geneb | Right genec | # SNPsd | P-valuee |
---|---|---|---|---|---|---|---|
5 | 8 432 269 | 10 486 082 | SEMA5A | MTRR | SNORD123 | 9 | 2 × 10−12 |
18 | 44 894 006 | 46 979 045 | MIR4320,MYO5B | ACAA2 | CCDC11 | 24 | 2 × 10−8 |
9 | 9 471 065 | 11 471 205 | PTPRD | JMJD2C | MPDZ | 2 | 3 × 10−8 |
14 | 22 917 791 | 24 973 124 | CBLN3,KHNYN,NFATC4,NYNRIN | CMTM5 | HCD1 | 5 | 5 × 10−8 |
4 | 167 781 602 | 169 841 939 | – | SPOCK3 | ANXA10 | 12 | 7 × 10−8 |
18 | 6 084 612 | 8 084 612 | LAMA1 | ARGHGAP28 | LRRC30 | 1 | 2 × 10−7 |
20 | 39 042 867 | 41 132 741 | – | CHD6 | PTPRT | 3 | 2 × 10−7 |
12 | 3 363 712 | 5 374 681 | – | FGF23 | FGF6 | 4 | 3 × 10−7 |
11 | 11 310 553 | 13 324 688 | MICALCL | MICAL2 | PARVA | 5 | 4 × 10−7 |
1 | 206 278 586 | 208 290 185 | KCNH1 | HHAT | RCOR3 | 8 | 5 × 10−7 |
The top 10 eQTL regions with the smallest association P-value are shown here with their chromosome locations, overlapping or nearest Refseq genes, number of SNPs along with the smallest P-value in each eQTL regions. The coordinates are based on human genome assembly NCBI36/hg18.
aeQTL gene that is located in the eQTL cluster. A “–” indicates that no gene overlaps the eQTL cluster.
beQTL gene that is located on the left side (p-terminal) of the eQTL cluster.
ceQTL gene that is located on the right side (q-terminal) of the eQTL cluster. Selected eQTL gene(s) bolded for each region.
dNumber of SNPs that are located in the eQTL cluster.
eMinimum P-value of association test of SEMA5A expression in the eQTL cluster.