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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Neuropharmacology. 2013 Feb 24;70:268–277. doi: 10.1016/j.neuropharm.2013.02.009

Table 1.

Analyses of correlation between CB1 receptor levels (X) in the prefrontal cortex (PFC), amygdala (AMY), striatum (STR), hippocampus (HIP) and midbrain (MID) and anxiety-related behavioral indices (Y) in the elevated plus maze (EPM), open field (OF) and social interaction (SI) in C57BL/6. For further details, see text.

X Y r2 p Slope Intercept-Y axis

PFC EPM Time in open arm (s) 0.88 0.06 −54.51 ± 14.31 57.15 ± 10.55
Time in center (s) 0.89 0.05 17.01 ± 4.14 22,69 ± 3.05
Head Dips (fz) 0.92 0.04 47.89 ± 9.73 53.32 ± 7.18

OF Total movement (cm) 0.79 0.11 −696.5 ± 252.2 1199 ± 186.0
Time in center (s) 0.50 0.29 −148.3 ± 104.2 170.0 ± 76.83
Rearing (fz) 0.40 0.36 −15.34 ± 13.16 16.02 ± 6.83

SI Total sniffing (s) 0.33 0.42 −35.97 ± 36.02 38.12 ± 18.69
Frontal sniffing (s) 0.74 0.14 −21.35 ± 8.87 18.42 ± 8.86
Abdominal sniffing (s) 0.36 0.40 −7.77 ± 7.35 6.43 ± 3.81
Anogenital sniffing (s) 0.01 0.93 −3.59 ± 34.89 12.83 ± 18.10

AMY EPM Time in open arm (s) 0.38 0.39 66.07 ± 60.02 −8.80 ± 21.22
Time in center (s) 0.65 0.19 26.69 ± 13.74 −1.64 ± 4.86
Head Dips (fz) 0.42 0.55 47.96 ± 56.38 −2.18 ± 20.39

OF Total movement (cm) 0.12 0.57 −566.6 ± 882.0 1098 ± 307.5
Time in center (s) 0.13 0.55 −261.4 ± 384.3 185.0 ± 134.0
Rearing (fz) 0.37 0.27 −31.90 ± 23.94 22.11 ± 8.346

SI Total sniffing (s) 0.10 0.60 −43.37 ± 74.82 51.49 ± 26.08
Frontal sniffing (s) 0.03 0.79 3.97 ± 13.57 6.49 ± 4.73
Abdominal sniffing (s) 0.07 0.66 9.11 ± 18.69 1.40 ± 6.51
Anogenital sniffing (s) 0.15 0.52 −52.64 ± 72.11 42.75 ± 25.14

STR EPM Time in open arm (s) 0.57 0.25 343.6 ± 212.8 −167.5 ± 118.1
Time in center (s) 0.45 0.33 106.6 ± 83.83 −47.79 ± 46.52
Head Dips (fz) 0.61 0.22 312.9 ± 177.7 −150.6 ± 98.62

OF Total movement (cm) 0.52 0.17 1545 ± 858.8 5.795 ± 516.1
Time in center (s) 0.05 0.73 158.9 ± 416.2 25.29 ± 250.1
Rearing (fz) 0.14 0.53 −17.46 ± 24.81 19.77 ± 14.91

SI Total sniffing (s) 0.23 0.41 −35.55 ± 37.07 64.72 ± 22.28
Frontal sniffing (s) 0.01 1.00 0.09± 35.87 9.95 ± 21.56
Abdominal sniffing (s) 0.11 0.59 12.35 ± 20.54 −1.14 ± 12.35
Anogenital sniffing (s) 0.15 0.52 −49.85 ± 68.99 57.41 ± 41.46

HIP EPM Time in open arm (s) 0.50 0.29 −135.8 ± 96.22 70.62 ± 39.66
Time in center (s) 0.64 0.20 −54.95 ± 28.87 31.47 ± 11.90
Head Dips (fz) 0.58 0.24 −135.6 ± 82.30 72.47 ± 33.92

OF Total movement (cm) 0.01 0.88 322.4 ± 1949 752.3 ± 803.3
Time in center (s) 0.03 0.82 −109.5 ± 419.0 108.6 ± 172.7
Rearing (fz) 0.37 0.39 144.8 ± 134.2 −33.90 ± 55.31

SI Total sniffing (s) 0.49 0.30 −105.1 ± 76.00 57.53 ± 31.32
Frontal sniffing (s) 0.42 0.35 −44.90 ± 37.40 26.70 ± 15.42
Abdominal sniffing (s) 0.43 0.34 −23.37 ± 18.99 13.09 ± 7.82
Anogenital sniffing (s) 0.57 0.25 −37.01 ± 22.88 18.55 ± 9.42

MID EPM Time in open arm (s) 0.72 0.07 211.9 ± 76.17 −97.52 ± 42.73
Time in center (s) 0.67 0.09 69.01 ± 27.91 −27.96 ± 15.66
Head Dips (fz) 0.64 0.11 174.4 ± 76.03 −76.54 ± 42.65

OF Total movement (cm) 0.02 0.80 508.1 ± 1879 611.0 ± 1054
Time in center (s) 0.30 0.34 517.2 ± 452.1 −199.5 ± 253.6
Rearing (fz) 0.44 0.23 −197.6 ± 129.7 130.1 ± 72.77

SI Total sniffing (s) 0.77 0.04 185.4 ± 57.80 83.26 ± 32.43
Frontal sniffing (s) 0.13 0.54 31.43 ± 46.02 −9.67 ± 25.82
Abdominal sniffing (s) 0.11 0.58 14.24 ± 23.45 −4.514 ± 13.16
Anogenital sniffing (s) 0.75 0.06 142.5 ± 47.93 −69.63 ± 26.89