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. 2013 Jun 24;8(6):e67324. doi: 10.1371/journal.pone.0067324

Table 2. Estimated cost and disease impact of pneumococcal vaccination with PCV10 and PCV13 in Kenyan infants born in 2010.

Without PCV10 PCV10 Introduction PCV13 Introduction
Pneumococcal disease episodes *
Meningitis 3,180 1,659 1,308
Sepsis 3,449 1,626 1,229
Bacteraemic pneumonia 6,221 3,602 3,027
Non-bacteraemic pneumonia 83,537 48,310 40,497
Total disease episodes 96,387 55,197 46,061
Total reduction in disease episodes 41,190 50,326
Pneumococcal deaths *
Meningitis 2,275 1,186 934
Sepsis 1,448 684 576
Bacteraemic pneumonia 2,612 1,513 1,270
Non-bacteraemic pneumonia 8,077 4,671 3,916
Total pneumococcal deaths 14,412 8,054 6,636
Total reduction in pneumococcal deaths 6,358 7,776
Pneumococcal vaccination costs (2010 US$)
Pneumococcal vaccine procurement cost $13,662,205 $13,662,205
Injection equipment cost (syringes, safety boxes) $360,306 $360,306
Annualized cold chain expansion costs $14,758 $70,714
Total costs of vaccination $14,037,268 $14,093,224
*

The number of pneumococcal deaths and episodes are non-discounted.