Figure 5. DNA and RNA Sensors are Transcriptionally Active in SLE Subsets.

A secondary analysis was performed with all normalized data in order to compare transcripts for specific pathways (19). (A) RNA sensing molecules (B) DNA sensing molecules and (C) downstream signaling and effector molecules were up-regulated in the three subsets as shown (Welch’s t-test, p<0.05*, p<0.01**, p<0.001***).