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. 2013 Jun 24;8(6):e66584. doi: 10.1371/journal.pone.0066584

Table 3. Genes associated with Antimicrobial resistance in BJAB07104, BJAB0868 and BJAB0715.

Genes Products Drug-resistant function Protein Locus Tag on BJAB genome
BJAB07104 BJAB0868 BJAB0715
aac A4 AAC (3)-I aminoglycoside acetyltransferase Aminoglycoside-modifying enzymes BJAB07104_p0002 BJAB0868_p0013
aac 3′-I Aminoglycoside N3′-acetyltransferase Aminoglycoside-modifying enzymes BJAB0715_p0027
aph A1-Iab Aminoglycoside phosphotransferase Aminoglycoside-modifying enzymes BJAB07104_p0020 BJAB0868_p0011
aphA6 Aminoglycoside phosphotransferase Aminoglycoside-modifying enzymes BJAB0715_p0002
aad A1 ANT (3″)-I aminoglycoside adenylyltransferase Aminoglycoside-modifying enzymes BJAB07104_p0004 BJAB0868_p0015
adeT RND (resistance-nodulation-division) family efflux pump Efflux pumps BJAB07104_01909 BJAB0868_02074
adeIJK RND (resistance-nodulation-division) family efflux pump Efflux pumps BJAB07104_03177-79 BJAB0868_03059-61 BJAB0715_03116-18
adeABC RND (resistance-nodulation-division) family efflux pump Efflux pumps BJAB07104_01911-15 BJAB0868_02068-72 BJAB0715_00260-64
abeM MATE (multidrug and toxic compound extrusion) family efflux pump Efflux pumps BJAB07104_00448 BJAB0868_00548 BJAB0715_00431
arm A 16S rRNA methylase Aminoglycoside-modifying enzymes BJAB07104_p0008 BJAB0868_p0019
str A Streptomycin resistance protein A Aminoglycoside-modifying enzymes BJAB07104_00282 BJAB0868_00382 BJAB0715_02883
Str B Streptomycin resistance protein B Aminoglycoside-modifying enzymes BJAB07104_00281 BJAB0868_00381 BJAB0715_02882
tet A(B) MFS (major facilitator superfamily) familyefflux pump Ttetracycline resistance protein BJAB07104_00277 BJAB0868_00377 BJAB0715_02878
TEM-1 Beta-lactamase class A β-lactamases BJAB0868_01360
ADC Beta-lactamase class C β-lactamases BJAB07104_02829 BJAB0868_02710 BJAB0715_02760
blaOXA-23 Beta-lactamase class D β-lactamases BJAB07104_02733 BJAB0868_00355 BJAB0715_03039
blaOXA-10 Beta-lactamase class D (OXA-51like) β-lactamases BJAB0715_01734,
blaOXA-66 Beta-lactamase class D (OXA-51like) β-lactamases BJAB07104_02182 OXA-66 BJAB0868_01795OXA-66
blaOXA-58 Beta-lactamase class D β-lactamases BJAB0715_p00053
cat B8 Chloramphenicol acetyltransferase Chloramphenicol resistance BJAB07104_p0003 BJAB0868_p0014
cm1A1 Chloramphenicol resistance protein Chloramphenicol resistance BJAB0715_p00013
mph (E) macrolide 2′-phosphotransferase Macrolide resistance BJAB07104_p0012 BJAB0868_p0023
msr E macrolide efflux protein Macrolide resistance BJAB07104_p0011 BJAB0868_p0022
sul 1 Dihydropteroate synthase Sulphonamides BJAB07104_p0005 BJAB0868_p0016
gyr A a DNA gyrase subunit A Fluoroquinolones BJAB07104_03067, R BJAB0868_02946, R BJAB0715_02991, R
par C b Topoisomerase IV subunit A BJAB07104_00229, S BJAB0868_00235, R BJAB0715_00241, S
a

R: Ser-Leu mutation at 83, S: no mutation at 83; b: R: Ser-Leu mutation at 84, S: no mutation at 84.