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. 2013 Jun 24;8(6):e61870. doi: 10.1371/journal.pone.0061870

Figure 4. Adult-induced Knockout of Mll2 does not result in a glucose phenotype.

Figure 4

A: Plasma glucose measured in an IPGTT in male mice at 12 weeks of age, Mll2 flox/+/tamoxifencre/+ Tamoxifen treated (N = 11) open circles, Mll2 flox/+/tamoxifencre/+ Vehicle treated (N = 10) black squares. B: Weight at 12 weeks of age, C: Fasted insulin at 12 weeks of age D: Relative expression of Mll2 gene after tamoxifen treatment in Liver, WAT, Pancreas and Skeletal muscle, mean of 8 biological replicates Mll2 flox/+/tamoxifencre/+ Tamoxifen (open bars) vs Mll2 flox/+/tamoxifencre/+ Vehicle (black bars) treated. Mean ± SEM, * p<0.05, **p<0.01, ***p<0.001, student's t-test.