Table 3. Ang-1, Ang-2, VEGF, Tie2 and NT-proBNP levels according to NYHA class, ventricular function and systemic ventricle physiology.

	Ang-1 (ng/ml)	Ang-2 (ng/ml	VEGF (pg/ml)	Tie2 (ng/ml)	NT-proBNP (pg/ml)
NYHA Class
I	5.8±3.8	2.5±1.6	111.4±62.5	19.9±3.3	128±200
II	6.5±5.7	6.8±6.6a	119.2±114.4	23.1±5.7	432±517a
III	4.5±3.2	8.2±6.9b	156.7±142.7	21.0±3.9	796±1081b,c
Ventricular function
normal	5.1±3.2	3.5±4.2	117.7±84.8	20.5±4.2	142±177
moderately impaired	6.7±5.5	5.3±5.1	128.6±111.1	21.0±4.1	394±477d
severely impaired	5.7±3.8	7.5±7.6e	122.2±110.8	23.2±4.4	1156±1540f
Systemic ventricle
right	7.5±7.3	4.9±5.2	117±85.5	21.6±4.2	642±758
left	5.6±3.4	2.9±2.8	116.9±81.6	20.1±3.7	180±250g
single	4.6±3.0	11.2±6.9h	144.5±145.9	23.1±5.4	617±1091i

Values are expressed as mean ± SD;

^ap<0.01 to NYHA I - Ang-2 and p<0.05 for NT-proBNP;

^bp<0.001 to NYHA I - Ang-2 and NT-proBNP;

^cp<0.05 for NT-proBNP and NYHA II;

^dp<0.01 vs. normal ventricular function;

^ep<0.05 vs. normal ventricular function;

^fp<0.01 vs. moderate ventricular dysfunction and p<0.001 vs. normal ventricular function;

^gp<0.01 vs. systemic right ventricle;

^hp<0.001 vs. systemic left and right ventricle;

ⁱp<0.01 vs. systemic left ventricle.