Figure 7. Maternal effect (lean versus obese mother): Relevant functions and diseases, and representation of the major network of interaction identified by IPA analysis of the genes differentially expressed between OP1 and OP2 obese mice.

The 35 genes differentially expressed between the obese mice born to lean and obese/diabetic mothers (F1LM and F2OM) obtained in the direct OP2/OP1 comparison were subjected to IPA analysis. The network shown contains 20 focal genes with a score of 50. The node color indicates the expression levels of genes: red, upregulated; green, downregulated.