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. Author manuscript; available in PMC: 2014 May 9.
Published in final edited form as: J Med Chem. 2013 Apr 29;56(9):3701–3709. doi: 10.1021/jm400228w

Table 2.

Kinetic data for GNT pAbs (pre-treated pAbs) and cocaine-treated GNT pAbs (post-treated pAbs)

pAbs kcat
(min−1)a
Km
(μM)
kcat/Km
(M−1 s−1)
kcat/kuncatb
Pre-treated pAbs 0.3143 61.85 84.69 7.67×104
Post-treated pAbs 0.1989 121.60 16.36 4.85×104
a

Reactions were carried out in PBS (pH 7.4) at 23 °C.

b

kuncat = 4.1 × 10−6 min−1.18