Table 2.

Associations between total bilirubin and measures of vascular calcified plaque and mortality (unadjusted and adjusted models) presented as beta (β) estimate and standard error (SE) for continuous traits and hazard ratio (HR) and 95 % confidence interval (CI) for discrete traits.

	Unadjusted		Partially Adjusted*		Fully Adjusted†
	β (SE)	p-value	β (SE)	p-value	β (SE)	p-value
CAC	0.784 (0.201)	<0.0001	0.121 (0.178)	0.50	0.163 (0.180)	0.37
CarCP	0.553 (0.200)	0.0056	0.158 (0.181)	0.38	0.188 (0.181)	0.30
AACP	0.199 (0.234)	0.39	-0.205 (0.209)	0.33	-0.111 (0.212)	0.60

	HR (CI)	p-value	HR (CI)	p-value	HR (CI)	p-value
All-cause mortality	2.06 (0.85-5.00)	0.11	1.29 (0.51-3.25)	0.60	1.59 (0.63-4.01)	0.32
CVD mortality	1.53 (0.40-5.89)	0.54	0.89 (0.23-3.57)	0.89	0.87 (0.23-3.34)	0.84
Non-CVD mortality	1.60 (0.86-2.99)	0.14	1.35 (0.72-2.55)	0.35	1.55 (0.82-2.92)	0.18

CAC = coronary artery calcified plaque, CarCP= carotid artery calcified plaque. AACP = abdominal aortic calcified plaque

^*adjusted for age, sex, BMI

^†adjusted for age, sex, BMI, T2D affected status, current smoking, hypertension, dyslipidemia