Table 3.
Proteins detected from patient specific spots
| Symbols | Protein Name | Acc. numbers | Function |
|---|---|---|---|
| S100A8 | Protein S100-A8 | S10A8_HUMAN | apoptosis |
| PPP2R1A | Serine/threonine-protein phosphatase 2A | 2AAA_HUMAN | apoptosis, chromosome segregation |
| HSPA9 | Stress-70 protein | GRP75_BOVIN | Chaperone, cell proliferation and aging |
| PDIA6 | Protein disulfide-isomerase A6 | PDIA6_HUMAN | Chaperone, isomerase |
| HSPD1 | 60 kDa heat shock protein | CH60_HUMAN | Chaperone, protein folding |
| HSPA1A | Heat shock 70 kDa protein 1A/1B | HSP71_HUMAN | Chaperone, protein folding |
| HSPA8 | Heat shock cognate 71 kDa protein | HSP7C_HUMAN | Chaperone, protein folding |
| LMNB2 | Lamin-B2 | LMNB2_HUMAN | structural molecule activity, lipodystrophy |
| TUBA | Tubulin alpha chain | TBA_XENTR | microtubule, structural molecule activity |
| TUBB2C | Tubulin beta-2C chain | TBB2C_HUMAN | microtubule, structural molecule activity |
| TUBB5 | Tubulin beta-5 chain | TBB5_HUMAN | microtubule, structural molecule activity |
| ACT | Actin, alpha sarcomeric/cardiac | ACT2_XENLA | cytoskeleton, cell motility |
| VIM | Vimentin | VIME_HUMAN | cytoskeleton, intermediate filaments |
| DES | Desmin | DESM_HUMAN | intermediate filament, cardiomyopathy |
| MYH7 | Myosin-7 | MYH7_HUMAN | contractile protein, hypertrophic CM |
| DSP | Desmoplakin | DESP_HUMAN | desmosomal protein, cardiomyopathy |
| PSMC5 | 26S protease regulatory subunit 8 | PRS8_HUMAN | degradation of ubiquitinated proteins |
| FHL1 | Four and a half LIM domains protein 1 | FHL1_HUMAN | muscle development, hypertrophy |
| FLG2 | Filaggrin-2 | FILA2_HUMAN | cell differentiation |
| DSG1 | Desmoglein-1 | DSG1_HUMAN | mediating cell-cell adhesion |
| MFGE8 | Lactadherin | MFGM_HUMAN | cell adhesion, angiogenesis |
| JUP | Junction plakoglobin | PLAK_HUMAN | Cell adhesion, cardiomyopathy, arrhythmia |
| CS | Citrate synthase | CISY_HUMAN | Carbohydrate metabolism, Tricarboxylic acid cycle |
| ACAA2 | 3-ketoacyl-CoA thiolase | THIM_HUMAN | apoptosis and mitochondrial damage |
| CKM | Creatine kinase M-type | KCRM_HUMAN | energy transduction |
| CKMT2 | Creatine kinase S-type | KCRS_HUMAN | energy transduction |
| ACOT1 | Acyl-coenzyme A thioesterase 1 | ACOT1_HUMAN | hydrolysis of acyl-CoAs |
| SLC25A4 | ADP/ATP translocase 1 | ADT1_HUMAN | exchange of ADP and ATP |
| ACAT1 | Acetyl-CoA acetyltransferase | THIL_HUMAN | ketone body metabolism |
| HADH | Hydroxyacyl-coenzyme A dehydrogenase | HCDH_HUMAN | Fatty acid metabolism |
| FH | Fumarate hydratase | FUMH_HUMAN | fumarate metabolic process |
| MAOB | Amine oxidase | AOFB_HUMAN | metabolism of neuroactive and vasoactive amines |
| MT-CO2 | Cytochrome c oxidase subunit 2 | COX2_HUMAN | electron transport |
| UQCRC1 | Cytochrome b-c1 complex subunit 1 | QCR1_HUMAN | electron transport, ATP |
| UQCRC2 | Cytochrome b-c1 complex subunit 2 | QCR2_HUMAN | electron transport, ATP |
| SAMM50 | Sorting and assembly machinery component 50 homolog | SAM50_HUMAN | mitochondrial function |
| NDUFS1 | NADH-ubiquinone oxidoreductase | NDUS1_HUMAN | NADH oxidation |
| PDHX | Pyruvate dehydrogenase protein X component | ODPX_HUMAN | pyruvate metabolic, acyltransferase activity |
| TUFM | Elongation factor Tu | EFTU_HUMAN | Elongation factor |
| ATP5A1 | ATP synthase subunit alpha | ATPA_HUMAN | oxidative phosphorylation |
| ATP5B | ATP synthase subunit beta | ATPB_HUMAN | oxidative phosphorylation |
| ATP5C1 | ATP synthase subunit gamma | ATPG_HUMAN | oxidative phosphorylation |
| DECR1 | 2,4-dienoyl-CoA reductase | DECR_HUMAN | Oxidoreductase |
| ALDH2 | Aldehyde dehydrogenase | ALDH2_HUMAN | Oxidoreductase |
| DLD | Dihydrolipoyl dehydrogenase | DLDH_HUMAN | Oxidoreductase |
| DLAT | Dihydrolipoyllysine-residue acetyltransferase- pyruvate dehydrogenase complex | ODP2_HUMAN | Oxidoreductase |
| DLST | Dihydrolipoyllysine-residue succinyltransferase-2-oxoglutarate dehydrogenase complex | ODO2_HUMAN | Oxidoreductase |
| ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway | ECSIT_HUMAN | Oxidoreductase |
| HSDL2 | Hydroxysteroid dehydrogenase-like protein 2 | HSDL2_HUMAN | Oxidoreductase |
| IDH2 | Isocitrate dehydrogenase | IDHP_HUMAN | Oxidoreductase |
| LDHA | L-lactate dehydrogenase A chain | LDHA_HUMAN | Oxidoreductase |
| MDH2 | Malate dehydrogenase | MDHM_HUMAN | Oxidoreductase |
| ACADM | Medium-chain specific acyl-CoA dehydrogenase | ACADM_HUMAN | Oxidoreductase |
| LDHD | Probable D-lactate dehydrogenase | LDHD_HUMAN | Oxidoreductase |
| AIFM1 | Apoptosis-inducing factor 1 | AIFM1_HUMAN | oxidoreductase, apoptosis |
| VDAC1 | Voltage-dependent anion-selective channel protein 1 | VDAC1_HUMAN | Oxidoreductase, apoptosis |
| ACADVL | Very long-chain specific acyl-CoA dehydrogenase | ACADV_HUMAN | Oxidoreductase, cardiomyopathy |
| PRKAR1A | cAMP-dependent protein kinase type I-alpha regulatory subunit | KAP0_HUMAN | Post-translational modification |
| PRKAR2A | cAMP-dependent protein kinase type II-alpha regulatory subunit | KAP2_HUMAN | Post-translational modification |
| LDB3 | LIM domain-binding protein 3 | LDB3_HUMAN | PKC-mediated signaling |
| PGK1 | Phosphoglycerate kinase 1 | PGK1_HUMAN | Kinase, transferase |
| PKM2 | Pyruvate kinase isozymes M1/M2 | KPYM_HUMAN | pyruvate, apoptosis, calcium signaling |
| PTRF | Polymerase I and transcript release factor | PTRF_HUMAN | caveolae formation, cell membrane repair |
| APOD | Apolipoprotein D | APOD_HUMAN | ligands transport |
| PACSIN3 | Protein kinase C and casein kinase substrate in neurons protein 3 | PACN3_HUMAN | vesicle formation and transport |
| SRL | Sarcalumenin | SRCA_HUMAN | regulation of calcium transport |
| FGB | Fibrinogen beta chain | FIBB_HUMAN | platelet aggregation |
| FGG | Fibrinogen gamma chain | FIBG_HUMAN | platelet aggregation |
| ANXA2 | Annexin A2 | ANXA2_HUMAN | stress response, exocytosis |
| ANXA6 | Annexin A6 | ANXA6_HUMAN | regulate intracellular Ca2+ release |
| ANXA11 | Annexin A11 | ANX11_HUMAN | cytokinesis |
| ANXA7 | Annexin A7 | ANXA7_HUMAN | membrane fusion, exocytosis |