FIGURE 1.
Vaccinia virus infection is fatal in STAT1−/− mice. WT and STAT1 −/− mice were infected with 2 × 106 pfu of VV intraperitoneally on day 0. (A) Survival was monitored over 10 days and the Kaplan-Meier plot of mouse survival is shown (n = 8). (B) 36 hr after infection, ovaries from infected mice were harvested and assayed for viral load. Data represents viral titer ± SD as pfu per ovary (n = 6).