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. 2013 Jun 24;8(6):e66926. doi: 10.1371/journal.pone.0066926

Table 3. Plasma levels of free amino acids and amino acid derivatives (µmol/100 mL) in rats after 50 weeks of diet administration.

Dietary supplementation1 Statistical significance of variance ratio (P)2, effects of
Control TTA FO TTA+FO TTA FO TTA*FO
Asparagine 9.85±2.03 14.85±2.69 12.87±3.99 16.89±2.01 <0.001 0.007 0.58
Arginine 8.87±1.57 5.60±1.37 10.29±2.51 8.30±2.10 <0.001 0.002 0.30
Aspartic acid 1.37±0.28 2.00±0.40 1.70±0.31 1.92±0.53 0.002 0.32 0.12
Citrulline 7.35±1.51 12.00±2.96 7.98±2.35 9.60±1.86 <0.001 0.22 0.04
Glutamine 53.85±5.04 71.64±13.26 60.11±9.97 71.30±8.88 <0.001 0.34 0.29
Glutamate 10.82±3.15 14.83±2.63 16.36±2.94 15.41±3.37 0.12 0.003 0.01
Glycine 23.44±4.87 37.46±11.88 25.08±3.28 40.11±11.65 <0.001 0.45 0.86
Histidine 5.93±0.80 15.67±6.99 8.06±1.66 11.39±1.53 <0.001 0.36 0.01
1-Methylhistidine 1.01±0.50 0.76±0.37 1.61±0.49 0.99±0.48 0.006 0.008 0.20
Phenylalanine 5.60±0.83 7.95±1.17 7.09±1.13 7.15±0.85 0.001 0.30 0.001
Serine 34.96±8.01 59.80±13.53 43.27±5.30 72.18±14.00 <0.001 0.005 0.56
Taurine 18.05±2.95 20.88±4.11 16.12±1.75 25.61±8.12 <0.001 0.37 0.04
Threonine 41.89±10.75 91.64±28.64 26.66±7.23 90.11±17.77 <0.001 0.15 0.24
Tryptophane 119±31.21 197±63.70 134±17.41 173±38.02 <0.001 0.74 0.14
Tyrosine 9.10±1.77 15.72±3.75 12.01±3.49 12.36±2.57 0.001 0.82 0.002
Valine 18.29±3.26 22.68±4.32 17.70±2.93 22.81±2.57 <0.001 0.83 0.73
Alanine 61.68±14.24 74.89±13.15 73.20±21.45 66.58±10.26 0.50 0.74 0.05
Cysteine 0.41±0.45 0.52±0.73 0.47±0.92 0.87±0.74 0.27 0.38 0.51
Isoleucine 7.20±1.34 7.86±1.58 6.53±1.30 7.69±1.27 0.04 0.34 0.57
Leucine 13.48±2.51 15.21±3.40 13.76±2.26 15.94±2.47 0.03 0.55 0.79
Lysine 53.16±6.03 45.19±11.06 54.60±12.19 46.67±6.26 0.01 0.62 0.99
Methionine 6.24±0.86 6.64±0.77 6.94±1.29 6.87±0.98 0.60 0.14 0.46
Ornithine 5.74±1.94 7.65±2.02 6.14±0.90 7.30±1.57 0.006 0.97 0.48
Phenylethylamine 7.43±1.27 6.72±1.24 6.21±1.56 7.59±1.01 0.42 0.67 0.02
Phosphatidylserine 2.80±0.34 3.09±0.78 3.03±0.51 3.03±0.38 0.42 0.61 0.40
Proline 32.69±7.51 36.18±10.47 36.77±11.35 31.14±8.55 0.50 0.86 0.08
1

Values are mean ± SD (n = 10).

2

P-values from two-way ANOVA, where TTA*FO denotes the interaction effect.