FIG. 1.
Representative diffusion-weighted images of the eyes of 1- and 3-month-old rd1 mice and age-matched wild-type mice (a–d). The retina/choroid complex (arrows) was hyperintense on all diffusion-weighted images. Nondiffusion-weighted images of the same mouse eyes show three MR-detected retinal layers, exhibiting dark (inner)—bright (middle)—dark (outer) signal intensity in wild-type and a single dark MR-detected retinal layer in rd1 retina (e–h). Arrow heads indicates the bright choroid layer. H&E stained slices of wild-type and rd1 mouse retinas show the absence of photoreceptor cells in rd1 mice (i–l).