Fig. 1.
Individual raw data profiles. a–g C57BL/6 mice were injected with 5 × 105 TC1 cells (n = 13–19 mice per group) on day 0. A unique dose of PBS or of 50 μg of CyaA-E7 was intravenously administered on day 4, 7, 11, 18, 25 or 30 (yellow line) (8). h–i C57BL/6 mice were injected with 5 × 105 MC38 cells (n = 12–21 mice per group) on day 0. A unique dose of PBS or a hydrodynamic injection of 10 μg of a plasmid codifying for murine IL-12 was administered on day 23 (yellow line) (25). Tumour size, computed as the mean of two perpendicular diameters, over time is represented for each mouse and each dosing group included in the study; 2 mm was considered as the limit of quantification (dashed line)