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. 2013 Apr 19;15(3):797–807. doi: 10.1208/s12248-013-9483-5

Table I.

Parameters of the Mathematical Model Developed

Parameter	CyaA-E7		IL-12
	Mean value	IAV (%)	Mean value	IAV (%)
	[2.5^th–97.5^th]	[2.5^th–97.5^th]	[2.5^th–97.5^th]	[2.5^th–97.5^th]
Ts₀ (mm)	0.324 [0.0796–0.572]	–	1.16 × 10⁻⁶ [5.57 × 10⁻⁷–2.35 × 10⁻⁶]	–
λ (mm · day⁻¹)	0.354 [0.325–0.381]	10.1 [4.9–13.4]	0.335 [0.306–0.362]	19.3 [11.3–24.4]
k ₁ (day⁻¹)	0.0907 [0.0842–0.118]	–	0.189 [0.101–0.615]	–
P(1)	0.844 FIX	–	0.844 FIX	–
k _{2_pop1} (day⁻¹)	0 FIX	–	0 FIX	–
k _{2_pop2} (day⁻¹)	0.0907 [0.0842–0.118]	–	0.189 [0.101–0.615]	–
k ₃ (au · day⁻¹)	1.08 [0.870–1.378]	–	1.08 FIX	–
k ₄ (day⁻¹)	0.0390 [0.0193–0.0771]	–	0.0390 FIX	–
REG₅₀ (mm)	3.18 [1.767–4.422]	33.8 [25.4–53.2]	2.08 [1.387–2.966]	36.1 [6.4–60.2]
γ	5.24 [3.673–6.781]	–	5.24 FIX	–
Residual error [Log (mm)]	0.206 [0.184–0.228]	–	0.168 [0.128–0.215]	–