Table 2.

IVM to study the dynamics of individual cells

Event	Organ	Probe	Reference
Neuronal morphology of hippocampal neurons	Brain	Thy1-GFP mice, dextran	Barretto et al., 2011
Neuronal circuitry	Brain	Brainbow mice	Livet et al., 2007
Dendritic spine development in the cortex	Brain	YFP H-line mice	Pan and Gan, 2008
Calcium imaging in the brain	Brain	GCAMP	Zariwala et al., 2012
Natural killer cell and cytotoxic T cell interactions with tumors	Xenograft	mCFP , mYFP	Deguine et al., 2010
Neutrophil recruitment in beating heart	Heart	Dextran, CX3CR1-GFP mice	Li et al., 2012
Immune cells in the central nervous system	Brain	Dextran, CX3CR1-GFP, LysM-GFP and CD11c-YFP mice	Nayak et al., 2012
Dendritic cells migration	Skin	YFP, VE-caherin RFP mice, dextran	Nitschké et al., 2012
CD8+ T cells interaction with dendritic cells during viral infection	Lymph nodes	EGFP, Dextran, SHG	Hickman et al., 2008
B cells and dendritic cells interactions outside lymph nodes	Lymph nodes	EGFP	Qi et al., 2006
Change in gene expression during metastasis	Xenograft		Pinner et al., 2009
Invasion and metastasis in head and neck cancer	Xenograft	YFP, RFP-lifeact, dextran	Amornphimoltham et al., 2013
Fibrosarcoma cell migration along collagen fibers	Dorsal skin chamber	SHG, EGFP, DsRed, Dextran	Alexander et al., 2008
Long term imaging mammary tumors and photo-switchable probes	Mammary window	Dendra-2	Kedrin et al., 2008; Gligorijevic et al., 2009
Long term imaging liver metastasis through abdominal window	Liver	SHG, Dendra2, EGFP	Ritsma et al., 2012b
Macrophages during intravasation in mammary tumors	Xenograft	EGFP, SHG, dextrans	Wang et al., 2007; Wyckoff et al., 2007
Melanoma collective migration	Dorsal skin Chamber	SHG, THG, EGFP, Dextran	Weigelin et al., 2012
Hematopoietic stem cells and blood vessel	Skullcup	Dextran	Lo Celso et al., 2009
Epithelial stem cells during hair regeneration	Skin	H2B-GFP mice	Rompolas et al., 2012