Table 2.
Regional distribution of mammary tumors in MMTV-cNeu transgenic mice
Cohort \ Glands | MG1/6 | MG2/7+3/8 | MG4/9+5/10 |
---|---|---|---|
A | 4 (15) | 19 (73)** | 3 (12) |
B | 11 (27) | 26 (63)** | 4 (10) |
Weight (%) | (18) | (46) | (36) |
(A) Number of palpable tumors observed in 21 tumor-bearing transgenic mice at the age of 9 months (% of 26 tumors total), and (B) number of tumors as assessed by necropsy in 22 mice at tumor endpoint (% of 41 tumors total). The relative wet weight of the specified glands in % is quoted from [52] and was not specifically determined for this strain. **P < 0.0001 compared to MG4/9 + 5/10 and to MG1/6 by mixed-effects Poisson regression analysis