Table 2.
Comparison of TPOAb+ and TPOAb− pregnant women with recurrent miscarriage. Data are expressed as mean±s.d. *indicates statistical significance (P<0.05).
| Parameter | TPOAb+ group (n=31) | TPOAb− group (n=69) | P value |
|---|---|---|---|
| Age (years) | 26.4±3.0 | 27.3±3.1 | 0.1 |
| Free T3 (ng/ml) | 3.2±2.8 | 2.5±0.7 | 0.06 |
| Free T4 (ng/ml) | 1.2±0.4 | 1.3±1.0 | 0.3 |
| TSH (μIU/ml) | 3.1±1.9 | 2.0±0.8 | 0.001* |
| TPOAb titre (IU/ml) | 105.0±150.6 | 18.5±9.6 | 0.001* |
| Gestation at delivery | 38.6±6.7 | 38.9±4.2 | 0.7 |
| Mode of delivery | |||
| Normal vaginal delivery | 24 (77%) | 51 (74%) | 0.7 |
| Operative vaginal delivery | 1 (3%) | 3 (4%) | |
| Lower segment caesarean section (LSCS) | 4 (13%) | 13 (19%) | |
| Missed abortion | 2 (7%) | 2 (3%) | |
| Complications | |||
| Abortion | 2 (7%) | 2 (3%) | 0.4 |
| Preterm labour (PTL) | 1 (3%) | 11 (16%) | 0.07 |
| Intrauterine growth retardation | 2 (7%) | 4 (6%) | 0.8 |
| Gestational hypertension | 2 (7%) | 4 (6%) | 0.8 |
| Intrahepatic cholestasis of pregnancy (ICP) | 1 (3%) | 4 (13%) | 0.031* |
| Postdatism | 3 (10%) | 3 (4%) | 0.2 |
| Preterm premature rupture of membranes | 0 | 1 (1%) | 0.5 |