Table 1.
The CCT2 and PDIA3 expression and clinicopathological features of gallbladder SC/ASC and AC
| Clinicalpathological features | SC/ASC (n = 46) | AC (n = 80) | χ2 | P |
|---|---|---|---|---|
| Gender |
|
|
|
|
| male |
19(41.3) |
26(32.5) |
0.986 |
0.352 |
| female |
27(58.7) |
54(67.5) |
||
| Age (years) |
|
|
|
|
| ≤ 45 |
3(6.5) |
16(20.0) |
4.143 |
0.042 |
| > 45 |
43(93.5) |
64(80.0) |
||
| Degree of differentiation |
|
|
|
|
| well-differentiated |
16(34.8) |
27(33.8) |
8.515 |
0.014 |
| moderately-Differentiated |
24(52.2) |
25(31.3) |
||
| poorly-differentiated |
6(13.0) |
28(35.0) |
||
| Tumor maximum diameter (cm) |
|
|
|
|
| ≤ 3 cm |
20(43.5) |
50(62.5) |
4.280 |
0.039 |
| > 3 cm |
26(56.5) |
30(37.5) |
|
|
| Gallbladder stones |
|
|
|
|
| no |
18(39.1) |
42(52.5) |
2.093 |
0.148 |
| yes |
28(60.9) |
38(47.5) |
||
| TNM stage |
|
|
|
|
| I+II |
12(26.1) |
21(26.3) |
0.287 |
0.866 |
| III |
20(33.5) |
38(47.5) |
||
| IV |
14(30.4) |
21(26.3) |
||
| Lymph node metastasis |
|
|
|
|
| no |
17(37.0) |
30(37.5) |
0.004 |
0.952 |
| yes |
29(63.0) |
50(62.5) |
|
|
| Invasion |
|
|
|
|
| no |
16(34.8) |
31(38.8) |
0.197 |
0.658 |
| yes |
30(62.5) |
49(61.3) |
||
| Surgical |
|
|
|
|
| radical |
14(30.4) |
26(32.5) |
0.215 |
0.898 |
| palliative |
18(39.1) |
28(35.0) |
||
| biopsy |
14(30.4) |
26(32.5) |
||
| average survival time |
10.07(4 to 25) |
10.34(3 to 27) |
0.014 |
0.906 |
| CCT2 |
|
|
|
|
| - |
23(50.0) |
31(46.2) |
0.165 |
0.685 |
| + |
23(50.0) |
49(53.8) |
|
|
| PDIA3 |
|
|
|
|
| - |
20(43.5) |
35(43.7) |
0.001 |
0.976 |
| + | 26(56.5) | 45(56.3) |