Table 4.
Variation of the cloning outcome depending on the type of genetic modification
| Genetic modification1 | Chance for pregnancy | Chance for delivery | Cloning efficiency (%) | No. of live cloned piglets | No. of healthy cloned piglets |
|---|---|---|---|---|---|
| HR |
1 |
4 |
3.8 |
2.3 |
0.6 |
| AGT |
1.8 |
6.2 |
4.2 |
3.5* |
1.5* |
| Replication of transgenic pigs | 1 | 2.4 | 3.9 | 2.7 | 1.2 |
Homologous recombination (HR) was used as the reference category. For details on the statistical analysis and definition of the cloning benchmarks listed, please see Methods.
* Statistically significant differences (p < 0.05).
1HR: homologous recombination, AGT: additive gene transfer, Replication of transgenic pigs: replication of already existing transgenic pig lines.