Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Target genes for homologous recombination
| Target gene | Vector | Modification |
|---|---|---|
|
CFTR[7]§ |
CH242-248P18 (>100 kb) |
ATG-STOP |
|
DMD[42]§ |
CH242-9G11 (>100 kb) |
Δ exon 52 |
|
GGTA1 |
CH242-21 F3 (>100 kb) |
ATG-STOP |
|
APC[64]§ |
12.5 kb |
STOP |
|
KRAS |
13.5 kb |
Point mutation |
| JAK3 | 13.8 kb | Δ exon 2-5 |
§ See indicated references.
